您的位置: 首页 > 农业专利 > 详情页

CARM1 inhibitors and uses thereof
专利权人:
Epizyme; Inc.
发明人:
Richard Chesworth,Oscar Miguel Moradei,Gideon Shapiro,Lei Jin,Robert E. Babine
申请号:
US15835758
公开号:
US10118931B2
申请日:
2017.12.08
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Provided herein are compounds of Formula (I):and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, wherein X, R1, R1a, R2a, R2b, R2c, R2d, are as defined herein, and Ring HET is a 6-membered monocyclic heteroaryl ring system of Formula:wherein L2, R13, G8, G10, G11, and G12 are as defined herein. Compounds of the present invention are useful for inhibiting CARM1 activity. Methods of using the compounds for treating CARM1-mediated disorders are also described.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
相关发明人
相关专利

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充