Michael J. Sailor,Guarav Abbi,Boycee E. Collins,Keiki-Pua S. Dancil
申请号:
US14491055
公开号:
US20150011521A1
申请日:
2014.09.19
申请国别(地区):
US
年份:
2015
代理人:
摘要:
A method of controlled in vivo drug delivery is provided. A porous silicon matrix having pores sized and configured to admit to trap and then release a predetermined molecular complex with a predetermined dose-time profile is selected. The matrix contains the predetermined molecular complex so that the predetermined molecular complex is disposed within the pores of the porous silicon matrix. The matrix is introduced into a human body. The drug releases according the dose-time profile. The introduction can be via transdermal introduction, intramuscular injection, intravenous introduction, surgical implantation, inhalation, and oral ingestion.