Ming Li,Roderike Pohl,Robert Feldstein,Robert Hauser,Errol De Souza
申请号:
US15347169
公开号:
US20170128542A1
申请日:
2016.11.09
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Stabilized glucagon formulations are provided, in the form of a clear solution. The formulations include glucagon in a non-aqueous diluent and an antioxidant The diluent and antioxidant are selected to provide a glucagon formulation with increased stability when compared to glucagon without the anti-oxidant and/or the diluent and which shows a comparable onset of action and duration of glucose response.The compositions can be used to treat subjects with very low blood sugar (severe hypoglycemia) that can happen in subjects who have diabetes and use insulin.