EGRISE, DOMINIQUE,GANGJI, VALERIE,HAUZEUR, JEAN-PHILIPPE,LAMBERMONT, MICHELINE,TOUNGOUZ, MICHEL
申请号：
CA2640794
公开号：
CA2640794C
申请日:
2007.02.16
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
The invention provides a method for obtaining osteoprogenitors, osteoblasts orosteoblast phenotype cells, as well as cell populations comprising such, fromhuman bone marrow stem cells in vitro or ex vivo, comprising contacting thebone marrow stem cells with human serum or plasma and a growth factor or abiologically active variant or derivative thereof. In addition, the inventionprovides novel osteoprogenitor or osteoblast phenotype cell types and cellpopulations comprising such, wherein such cell populations may comprisefurther cell types, such as preferably endothelial cells or progenitors. Inrelated aspects, the invention provides uses, in particular in the field oftherapy, preferably bone therapy, of the above methods, cells and cellpopulations obtainable using the methods, and of the cell types and cellpopulations specifically described herein.
