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COMBINATION OF TGF-.BETA. INHIBITION AND IMMUNE STIMULATION TO TREAT HYPERPROLIFERATIVE DISEASES
专利权人:
BIOGNOSTIK GESELLSCHAFT FUR BIOMOLEKULARE DIAGNOSTIK MBH
发明人:
SCHLINGENSIEPEN, KARL-HERMANN,SCHLINGENSIEPEN, REIMAR,BRYSCH, WOLFGANG
申请号:
CA2334960
公开号:
CA2334960C
申请日:
1999.06.10
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
Medicament comprising a combination of- at least one inhibitor of the effect of a substance negatively effecting animmuneresponse, the substance selected from the group consisting of TGF-.beta. andits receptors,VEGF and its receptors, interleukin 10 (IL-10) and its receptors, PGE2 and itsreceptors, wherein the inhibitor has a molecular weight of less than 100 kDaand- at least one stimulator positively effecting an immune response.
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