A patient connection system for peritoneal dialysis is described. The system comprises: a housing (12) a fill container occluder valve (14a) carried within the housing for receiving a fill container line (16a) connected to a fill container (18a) a drain container occluder valve (14b) carried within the housing for receiving a drain container line (16b) connected to a drain container (18b) a shunt spike (22) held by the housing and translatably mounted thereon for simultaneously and removably fluidly connecting to the fill container line and the drain container line to allow fresh dialysis fluid to run from the fill container to the drain container to prime the fill container line when the fill and drain container occluder valves are open and a patient transfer set holder provided by the housing, the patient transfer set holder configured to allow a patient transfer set (24) to be connected to the fill container line after the fill and drain container occluder valves have been closed and the shunt spike has been disconnected from the fill and drain container lines.本発明は腹膜透析接続装置を提供し得る。上記腹膜透析(「PD」)接続装置は、PD流体充填ラインに接続するための第1のコネクタと、第1のコネクタと流体連通する第2のコネクタであって、空気は通過させるが、流体は通過させないように構成される、フィルタを含む、第2のコネクタと、選択的にフィルタに曝露し、患者の腹膜内に捕捉された空気を大気中に放出させるように、手動で除去可能かつ第2のコネクタに再密閉可能な気密キャップとを含む。