COMPOSITION FOR ELICITING A SPECIFIC CTL RESPONSE, COMPRISING A LYMPHO-ABLATIVE COMPOUND AND A MOLECULE THAT CONTAINS ANTIGENIC SEQUENCES AND TARGETS PROFESSIONAL ANTIGEN PRESENTING CELLS
The present invention relates to a composition for eliciting a specific cytotoxic T lymphocyte (CTL) response against T cell epitopes in a mammal, which comprises a compound provoking lymphocytopenia, a molecule having selective affinity for professional antigen presenting cells (APC), wherein said molecule is associated to said T cell epitope, and optionally, a pharmaceutical acceptable carrier. Advantageously, the composition further contains an adjuvant. Said composition may be used in anti-infections and anti-cancer therapies.
