603575 Disclosed herein are compounds of formula (I), wherein the variables are defined in the specification, and the use of said compounds in the treatment of a urinary excretion disorder and/or improving the symptoms thereof. The compounds are disclosed to have ENPP2 inhibitor activity. In one embodiment the compound is cis-4-(2-{ 9-[(2,5-dimethyl-1,3-thiazol-4-yl)methyl]-1,3,4,9-tetrahydro-2H-&bgr-carbolin-2-yl} -2-oxoethyl)cyclohexanecarboxylic acid.
