DEGOEY DAVID A.,KATI WARREN M.,HUTCHINS CHARLES W.,DONNER PAMELA L,KRUEGER ALLAN C.,RANDOLPH JOHN T.,MOTTER CHRISTOPHER E.,NELSON LISSA T.,PATEL SACHEL V.,MATULENKO MARK A.,KEDDY RYAN G.,JINKERSON TAM,Degoey David A.,Kati Warren M.,Hutchins Charles W.,Donner Pamela L,Krueger Allan C.,Randolph John T
申请号：
SI201130697
公开号：
SI2692346T1
申请日:
2011.10.12
申请国别(地区):
SI
年份:
2016
代理人:
摘要：
PROBLEM TO BE SOLVED: To provide a compound that is effective in inhibiting the function of non-structural protein NS5A which is an essential component in the replication of C type hepatitis virus ("HCV").SOLUTION: Provided is a compound exemplified by methyl{(2S,3R)-1-[(2S)-2-{5-[(2R,5R)-1-{3,5-difluoro-4-[4-(4-fluorophenyl)piperidine-1-yl]phenyl}-5-(6-fluoro-2-{(2S)-1-[N-(methoxycarbonyl)-O-methyl-L-threonyl]pyrrolidin-2-yl}-1H-benzimidazole-5-yl) pyrrolidin-2-yl]-6-fluoro-1H-benzimidazole-2-yl}pyrrolidin-1-yl]-3-methoxy-1-oxobutanoic-2-yl}carbamate or the like, or a pharmaceutically acceptable salt thereof and a derivative thereof.SELECTED DRAWING: None
