MIYAJI, KATSUAKI,宫地克明,宮地克明,IWAMOTO, SHUNSUKE,岩本俊介,NAKANO, SATOSHI,中野智,OTA, HIROFUMI,太田博史,SHIGETA, YUKIHIRO,繁田幸宏,HIROKAWA, YUTAKA,广川裕,廣川裕,YANAGIHARA, KAZUFUMI,柳原一史,TOYAMA, KOJI
申请号:
TW094144339
公开号:
TWI399368B
申请日:
2005.12.14
申请国别(地区):
TW
年份:
2013
代理人:
摘要:
The present invention provides a kind of thrombopoietin receptor activation and is effective disease prevention, treatment or improves effective compounds.The compounds are formula (1) (A, B, R1 in formula,L1,R2,L2,L3,Y,L4,R3, X indicate this specification institute definien) shown in compound, the compounds tautomeric of the compound, forerunner's drug or its medically can received salt or they solvate.本發明提供一種血小板生成素受體活性化作用為有效之疾病預防、治療或改善有效之化合物類。該化合物類為式(1)(式中A、B、R1、L1、R2、L2、L3、Y、L4、R3、X表示本說明書所定義者)所示化合物、該化合物之互變異構物、前驅藥物或其醫學上可被接受的鹽或彼等之溶劑合物。