Vittoria ZINZALLA,Klaus-Peter KUENKELE,Marie-Ange BUYSE,Karen CROMIE,Stephanie STAELENS,Beatrijs STRUBBE
申请号：
US15992345
公开号：
US20180344868A1
申请日:
2018.05.30
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The invention provides novel LRP5-binding polypeptides, and more specifically novel LRP5-binding immunoglobulin single variable domain constructs which can inhibit Wnt signaling pathways. The invention also relates to specific sequences of such polypeptides, methods of their production, and methods of using them, including methods of treatment of diseases such as cancer.
