The present invention relates to a Brk-inhibiting compound represented by the general formula (I) (wherein all symbols have the same meanings as those described in the specification), a salt thereof, an N-oxide thereof, and a solvate thereof. , Or their prodrugs.本発明は、一般式(I)(式中、すべての記号は、明細書記載の記号と同じ意味を表す。)で示されるBrk阻害化合物、その塩、そのN-オキシド体、その溶媒和物、またはそれらのプロドラッグに関する。