Sinusitis and other disorders of the ear, nose and throat are diagnosed and/or treated using minimally invasive approaches with flexible or rigid instruments. Various methods and devices are used for remodelling or changing the shape, size or configuration of a sinus ostium or duct or other anatomical structure in the ear, nose or throat implanting a device, cells or tissues removing matter from the ear, nose or throat delivering diagnostic or therapeutic substances or performing other diagnostic or therapeutic procedures. Introducing devices may be used, comprising a introducing member having a proximal end and a distal end for insertion into in a nasal cavity and a working device that can be advanced along the introducing member, wherein the working device comprises a balloon catheter comprises radiographic markers.