LANMAN, BRIAN ALAN,CEE, VICTOR J.,PICKRELL, ALEXANDER J.,REED, ANTHONY B.,YANG, KEVIN C.,KOPECKY, DAVID JOHN,WANG, HUI-LING,LOPEZ, PATRICIA,ASHTON, KATE,BOOKER, SHON,TEGLEY, CHRISTOPHER M.
申请号:
CA3048217
公开号:
CA3048217A1
申请日:
2017.12.21
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
Provided herein are benzisothiazol, isothiazolo[3,4-b]pyridine, quinazoline, phthalazine, pyrido[2,3-d]pyridazine and pyrido[2,3-d]pyrimidine derivatives and related compounds as KRAS G12C inhibitors for treating e.g. lung cancer, pancreatic cancer or colorectal cancer.