A blood pressure measurement device includes a body, a film-type pressure sensing unit, a first electrode, and a second electrode. The body includes a pulse sensing surface and a concave portion. The film-type pressure sensing unit is disposed on the pulse sensing surface and communicated with the concave portion. The first electrode is disposed on the pulse sensing surface. The second electrode is disposed on the body corresponding to the first electrode. The first electrode and second electrode are a pair of ECG electrodes. A blood pressure measurement method cooperated with the blood pressure measurement device is also disclosed.