PEPTIDES DERIVED FROM HOMEOBOX PROTEIN B13 (HOX-B13) AND COMPLEXES COMPRISING SUCH PEPTIDES BOUND TO MHC MOLECULES

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专利权人:

IMMUNOCORE LIMITED;ADAPTIMMUNE LIMITED

发明人:

Alex POWLESLAND,Meidai SUN

申请号：

US15777875

公开号：

US20180339029A1

申请日:

2016.11.23

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The present invention relates to novel peptides derived from Homeobox protein Hox-B13 (HOXB13), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.

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中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/