A medication storage lock box that can be easily opened in an emergency includes a storage chamber to which a lid is hingeably connected. A severable strap couples the lid to a clasp that engages the locking mechanism of a combination lock. The lid may be opened either by entering the proper lock combination and releasing the clasp or, in a medical emergency caused by the owner becoming incapacitated or forgetting the combination of the lock, by cutting the strap which couples the lid to the clasp. The lock box may be made of materials such as leather, imitation leather, fiberboard-reinforced fabric, fiberboard, thermoplastic resins, thermosetting resins, or resin impregnated paper.(112)