Robyn PURO,Pamela T. MANNING,Robert W. KARR,Ronald R. HIEBSCH,Benjamin J. CAPOCCIA,Gabriela ANDREJEVA
申请号：
US16682893
公开号：
US20200297842A1
申请日:
2019.11.13
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Anti-SIRPα monoclonal antibodies (anti-SIRPα mAbs), including multispecific SIRPα antibodies, are provided with distinct functional profiles as are related compositions and methods of using anti-SIRPα mAbs as therapeutics for the prevention and treatment of solid and hematological cancers. Also provided are amino acid sequences of exemplary anti-SIRPα monoclonal antibodies.
