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Mouthwashes of non-alcoholic bioactive essential oils
专利权人:
Johnson & Johnson Consumer Inc.
发明人:
Mordas, Carolyn,Gambogi, Robert J.
申请号:
ES11172281
公开号:
ES2688569T3
申请日:
2011.06.30
申请国别(地区):
ES
年份:
2018
代理人:
摘要:
An antimicrobial mouthwash composition with reduced alcohol comprising: a. an oil phase comprising one or more antimicrobial essential oils; b. a solvent system comprising at least one polyol solvent and at least one sugar alcohol solvent; c. at least one alkyl sulfate surfactant; d. optionally, at least one additional surfactant; and e. an aqueous phase comprising water in which the total amount of polyol solvent is in an amount of 5.0% to 15.0% w / v of the composition, in which the total amount of sugar alcohol solvent is in an amount of 5.0% to 15.0% w / v of the composition, and; wherein the total amount of solvent system is in an amount of 10% to 20% w / v of the composition, and; wherein the mouthwash composition is a microemulsion comprising micelles having an aggregate size of less than about 200 nm, in which the size of the aggregate is measured using the methods described in the description and; wherein the composition contains up to 5% by weight of the compounds that affect total bioavailability, in which the compounds that affect bioavailability are compounds selected from the group consisting of polyethylene oxide / oxide oxide block copolymers. polypropylene such as poloxamers, cyclodextrins, polysorbates and mixtures thereof, and; wherein the composition contains up to 10% v / v of the total composition of C2 to C4 monohydric alcohols.Una composición de enjuague bucal antimicrobiana con alcohol reducido que comprende: a. una fase oleosa que comprende uno o más aceites esenciales antimicrobianos; b. un sistema solvente que comprende por lo menos un solvente de poliol y por lo menos un solvente de alcohol de azúcar; c. por lo menos un surfactante de sulfato de alquilo; d. opcionalmente, por lo menos un surfactante adicional; y e. una fase acuosa que comprende agua en la que la cantidad total de solvente de poliol está en una cantidad del 5,0% al 15,0% p/v de la composición, en la que la cantidad total de solvente de alcohol de azúcar está en una cantid
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