The present invention relates to the field of modifying Jatropha disease resistance. More specifically, the present invention relates to a method for enhancing Jatropha curcas virus resistance by transgenic expression of a hairpin construct, which comprises sequences homologous to two or more key geminivirus DNA-A genes encoding replication initiator protein (Rep AC1), transcriptional activator protein (TrAP ACT), replication enhancer protein (REn AC3), gene silencing suppressor (AC4) and coat protein (CP, AV1). The plants having virus resistance can be used for Jatropha breeding..
