The Board of Regents of the University of Texas System
发明人:
Sean MORRISON,Rui YUE
申请号:
US15567762
公开号:
US20180110832A1
申请日:
2016.04.18
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present disclosure describes the C-type lectin CLEC11a as a bone growth factor. Clec11a-deficient mice showed reduced bone volume and mineralization, while bone resorption remained unchanged. Administration of recombinant Clec11a systemically promoted bone formation in mice at risk for osteoporosis.