Shanghai Hengrui Pharmaceutical Co., Ltd;Jiangsu Hengrui Medicine Co., Ltd.
发明人:
FANG, Jingjing,YAN, Zhen,TONG, Guimei,LIU, Xun
申请号:
AU2018280485
公开号:
AU2018280485A1
申请日:
2018.06.05
申请国别(地区):
AU
年份:
2020
代理人:
摘要:
A stable c-Met antibody-drug conjugate (c-Met ADC) formulation and use thereof in medicine are described. In particular, the formulation contains c-Met ADC, a buffer, and can also contains at least one stabilizer, and optionally a surfactant. The c-Met ADC formulation of the application can effectively inhibit the aggregation and isomerization of antibodies, and prevent the degradation of an antibody product therein, being a stable injectable pharmaceutical formulation.