BAE, IN HO,배인호,KIM, JONG MIN,김종민,LIM, KYUNG SEOB,임경섭,PARK, DAE SUNG,박대성,KIM, HYUNG KEUN,김형근,JEONG, MYUNG HO,정명호
申请号：
KR1020120006767
公开号：
KR1011986420000B1
申请日:
2012.01.20
申请国别(地区):
KR
年份:
2012
代理人:
摘要：
PURPOSE: A restenosis prevention multilayer coating stent and a manufacturing method thereof are provided to improve solubility in an organic solvent and to suppress the growth of cells.CONSTITUTION: A restenosis prevention multilayer coating stent comprises a first coating layer including fucoidan, and a second coating layer including poly(lactic-co-glycolic acid). In the first coating layer, fucoidan is distributed in the content of 50-500 ug/stent. The release speed of the fucoidan is controlled by laminating the second coating layer on the surface of the first coating layer. The total thickness the coating layer of the stent is 0.01-100 micrometers.COPYRIGHT KIPO 2013[Reference numerals] (AA) Metal stent (BB) Concentration of fucoidan coated on metal stent본 발명은 재협착 방지용 다층 코팅 스텐트 및 이의 제조방법에 관한 것으로, 상기 스텐트는 대동맥 혈관 평활근 세포증식 억제와 혈관확장 활성이 있어, 스텐트 내 재협착을 방지하고 치료에 유용하여 시술 후 용이하게 재협착을 방지 및 치료할 수 있는 장점이 있다.
