Some embodiments of the current disclosure are directed toward physiological monitoring systems, devices and methods for implementation as wearable and/or wireless sensor(s) and to be used in aiding clinicians in the diagnosis and identification of various clinical conditions, events and/or trends. The systems and devices include an RF device configured to transmit radio-frequency (RF) waves towards an artery located within a tissue of a patient or a subject and to receive reflected RF waves from the artery. In some embodiments, the reflected RF waves are analyzed to determine various physiological conditions of the subject including but not limited to blood pressure, heart rate, arrhythmic events, and/or the like.
