The invention concerns the use of at least one fungal polysaccharide comprising for the major part a chitin-glucan copolymer, for making an orally administered composition. In particular, the invention concerns a pharmaceutical composition or food complements for preventing, treating or controlling in particular dyslipidemia, hypercholesterolemia, atherosclerosis, and for stimulating antioxidant activities of the organism to stimulate the immune system, perform a hypoglycemic action beneficial in the case of diabetes, and promoting satiety to minimise the metabolic syndrome.