Peter R. Brink,Michael R. Rosen,Richard B. Robinson,Ira S. Cohen,Arthur Grollman
申请号:
US12910346
公开号:
US08188062B2
申请日:
2010.10.22
申请国别(地区):
US
年份:
2012
代理人:
摘要:
A method of delivering an oligonucleotide or a plasmid expressing an oligonucleotide into a target cell comprises introducing an oligonucleotide into a donor cell, particularly a stem cell, and contacting the target cell with the donor cell under conditions permitting the donor cell to form a gap junction with the target cell, whereby the oligonucleotide or a product of the oligonucleotide is delivered into the target cell from the donor cell.