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Device and method for creating aerosols for drug delivery
专利权人:
Alfonso M. Ganan-Calvo
发明人:
Alfonso M. Ganan-Calvo
申请号:
US11926936
公开号:
US08733343B2
申请日:
2007.10.29
申请国别(地区):
US
年份:
2014
代理人:
摘要:
A drug delivery device is disclosed which produces aerosolized particles of pharmaceutically active drug for delivery to a patient by inhalation. The device includes a liquid feeding source such as a channel to which formulation is added at one end and expelled through an exit opening. The feeding channel is surrounded by a pressurized chamber into which gas is fed and out of which gas is expelled from an opening. The opening from which the gas is expelled is positioned directly in front of the flow path of liquid expelled from the feeding channel. Various parameters are adjusted so that pressurized gas surrounds liquid flowing out of the feeding channel in a manner so as to maintain a stable capillary microjet of liquid until the liquid exits the pressure chamber opening and is aerosolized into particles having a uniform diameter in the range of about 1 to 5 microns.
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