M. Maral Mouradian,Steven Braithwaite,Michael Voronkov
申请号:
US15909576
公开号:
US20180185355A1
申请日:
2018.03.01
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Methods of treating patients with dyskinesias, by administering a therapeutically effective amount of a dual-action μ-opioid receptor antagonist/-ϰ-opioid receptor agonists or prodrug thereof to a subject in need thereof, sufficient to mitigate the dyskinesia. Alternatively, a combination of both a μ-opioid receptor antagonist or prodrug thereof, and a ϰ-opioid receptor agonist or prodrug thereof can be administered, either together or separately.