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COMBINATION DRUG THERAPIES FOR CANCER AND METHODS OF MAKING AND USING THEM
专利权人:
发明人:
Newell Bascomb,John Maki,Fredric Young
申请号:
US15829460
公开号:
US20180169067A1
申请日:
2017.12.01
申请国别(地区):
US
年份:
2018
代理人:
摘要:
In alternative embodiments, provided are therapeutic combinations, pharmaceutical compositions, formulations, kits and devices for treating, preventing or ameliorating a tumor or a cancer, and methods and uses for treating, preventing or ameliorating a tumor or a cancer. In alternative embodiments, provided are therapeutic combinations, pharmaceutical compositions, formulations, kits and devices comprising: a beta adrenergic receptor antagonist (a “beta blocker”) such as propranolol a non-steroidal anti-inflammatory drug (a NSAID) such as etodolac and, a sorafenib or NEXAVAR™ or equivalent thereof In alternative embodiments, the therapeutic combinations further comprise an anti-cancer or anti-tumor antibody, a cytokine, and/or an additional chemotherapeutic agent. In alternative embodiments, the methods, uses, therapeutic combinations, pharmaceutical compositions, formulations, kits and devices are used for treating, preventing or ameliorating a hepatocarcinoma or hepatocellular carcinoma (HCC), an adenocarcinoma, a metastatic adenocarcinoma of the liver, or an advanced hepatocellular carcinoma.
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