4-AMINO-3-(IMIDAZOLYL)-PYRAZOLO[3,4-D]PYRIMIDINES

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专利权人:

INC.;CHEMOCENTRYX

发明人:

ZHANG, PENGLIE,ZENG, YIBIN

申请号：

EP09813627

公开号：

EP2323663A4

申请日:

2009.09.10

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are 4-amino-3-imidazoyl-pyrazolo[3,4-d]pyrimidine derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated disease, and as controls in assays for the identification of competitive CCR1 antagonists.

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