CORCEPT THERAPEUTICS INC.;Joseph K. BELANOFF;Andreas G. MORAITIS;Pejman COHAN
发明人:
Joseph K. BELANOFF,Andreas G. MORAITIS,Pejman COHAN
申请号：
IL25478717
公开号：
IL254787D0
申请日:
2017.09.28
申请国别(地区):
IL
年份:
2017
代理人:
摘要：
This invention provides for a method of treating secondary adrenal insufficiency by co-administrating therapeutically effective amounts of a glucocorticoid and a glucocorticoid receptor antagonist to the patient in need thereof. In some embodiments, the method includes the proviso that the patient not be otherwise in need of treatment with a glucocorticoid and a glucocorticoid receptor antagonist. The treatment method can increase the patient's morning or basal cortisol level to at least about 12 μg/dL or a standard control level, and in turn, expedite significantly the recovery of the HPA axis. The method provided herein can improve health outcomes and life-threatening complications associated with secondary adrenal insufficiency.
