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Stabilized formulations containing anti-interleukin-6 receptor (IL-6R) antibodies
专利权人:
Daniel B. Dix;Scott M. Walsh;Douglas Kamen;Kenneth S. Graham
发明人:
Daniel B. Dix,Kenneth S. Graham,Douglas Kamen,Scott M. Walsh
申请号:
US12986223
公开号:
US09173880B2
申请日:
2011.01.07
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention provides pharmaceutical formulations comprising a human antibody that specifically binds to human interleukin-6 receptor (hIL-6R). The formulations may contain, in addition to an anti-hIL-6R antibody, at least one amino acid, at least one sugar, and/or at least one non-ionic surfactant. The pharmaceutical formulations of the present invention exhibit a substantial degree of antibody stability after storage for several months.
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