Avigen, Inc.;The Regents of The University of Colorado, A Body Corporate
发明人:
JOHNSON, KIRK W.,WATKINS, LINDA,HUTCHINSON, MARK
申请号：
PL08724934
公开号：
PL2131841T3
申请日:
2008.01.29
申请国别(地区):
PL
年份:
2013
代理人:
摘要：
Methods of potentiating opioid-induced analgesia in a subject by administration of a phosphodiesterase (PDE) inhibitor or glial attenuator are described. In particular, the present invention is directed to methods of treating or preventing acute or subchronic pain by administration of a PDE inhibitor or glial attenuator, such as ibudilast (3-isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine), in combination with an opioid.
