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Therapeutic uses of rubber putty
专利权人:
Regenera Pharma Ltd.
发明人:
HAZAN, Zadik
申请号:
ES10712171
公开号:
ES2617875T3
申请日:
2010.03.04
申请国别(地区):
ES
年份:
2017
代理人:
摘要:
An isolated fraction of the putty gum, the fraction comprising the polymeric myrcene and being obtainable by: a) contacting the putty gum with at least one polar organic solvent; b) isolate a fraction that is soluble in the at least one polar organic solvent; c) treating the soluble fraction obtained in step b) with at least one non-polar organic solvent selected from a C5-C10-alkane, d) isolating a fraction that is soluble in said non-polar organic solvent, in which the steps to ) ab) and c) ad) are each carried out independently of a number of cycles, in which the fraction is substantially devoid of compounds that are soluble in said polar organic solvent but insoluble in said non-polar organic solvent, in which At least one polar organic solvent is an alcohol selected from the group consisting of methanol, ethanol, propanol, isopropanol, 1-butanol, 2-butanol, sec-butanol, t-butanol, 1-pentanol, 2-pentanol, 3-pentanol , neopentanol, 3-methyl-1-butanol, 2-methyl-1-butanol, 3-methyl-2-butanol, 2-methyl-2-butanol, ethylene glycol, and ethylene glycol monomethyl ether, and mixtures thereof, for use in the treatment of an altered neurological function, in which neurological function altered comprises a decrease in a function selected from the group consisting of cognitive function, sensory function, motor function and combinations thereof.Una fracción aislada de la goma de masilla, comprendiendo la fracción el mirceno polimérico y siendo obtenible por: a) poner en contacto la goma de masilla con al menos un disolvente orgánico polar; b) aislar una fracción que es soluble en el al menos un disolvente orgánico polar; c) tratar la fracción soluble obtenida en la etapa b) con al menos un disolvente orgánico no polar seleccionado de un C5-C10-alcano, d) aislar una fracción que es soluble en dicho disolvente orgánico no polar, en el que los pasos a) a b) y c) a d) se llevan a cabo cada uno independientemente de un número de ciclos, en el que la fracción está sustancialmente
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