ACADEMISCH MEDISCH CENTRUM;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
发明人:
JORGENSEN, CHRISTIAN,TAK, PAUL PETER
申请号:
DK04774913
公开号:
DK1664315T3
申请日:
2004.09.01
申请国别(地区):
DK
年份:
2012
代理人:
摘要:
The present invention relates to the field of adeno-associated virus (AAV) based gene therapy, in particular in vivo gene therapy, of rheumatoid arthritis (RA). The invention provides recombinant AAV virions being highly efficient in delivering genes encoding therapeutic proteins to the arthritic joints, and methods for using such virions in in vivo gene therapy.