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BIRD FLU VACCINE COMBINATION COMPRISING VIRUS-LIKE PARTICLES AND NOVEL ADJUVANTS
专利权人:
Academia Sinica
发明人:
Shu-Mei LIANG,Pei-Wen HSIAO,Ming-Chu CHENG,Yu-Chih YANG
申请号:
US15756774
公开号:
US20180243402A1
申请日:
2016.09.09
申请国别(地区):
US
年份:
2018
代理人:
摘要:
A vaccine composition is disclosed. The vaccine composition comprises: (a) a therapeutically effective amount of an influenza virus-like particle (VLP) comprising: (i) influenza M1, influenza M2, influenza hemagglutinin (HA), and influenza neuraminidase (NA) proteins; (b) Foot-and-mouth disease virus (FMDV) capsid protein VP3, recombinant FMDV VP3 (rVP3), VP3 peptide, or SUMO VP3; and (c) alum. Also disclosed is use of a vaccine composition according to the invention in the manufacture of a medicament for inducing an immunogenic response in a subject in need thereof.
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