THERAPEUTIC NANOPARTICLES CONTAINING A THERAPEUTIC AGENT AND METHODS FOR PRODUCING AND USING THEM

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专利权人:

ПФАЙЗЕР ИНК. (US)

发明人:

ЗЕЙЛ, Стефен Э. (US)

申请号：

RU2018129118

公开号：

RU2018129118A

申请日:

2017.02.10

申请国别(地区):

RU

年份:

2020

代理人:

摘要：

The present disclosure generally relates to nanoparticles comprising an antibody, such as an anti-PD-1 antibody. Other aspects include methods of making and using such nanoparticles. In an embodiment, the nanoparticles comprise a diblock poly(lactic) acid-poly(ethylene)glycol (PLA-PEG) copolymer, a chemotherapeutic agent, and a prostate-specific membrane antigen (PSMA) targeting ligand.

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