Erica Jean Philips;Jeffrey Keeler Teumer;Jizeng Qiao
发明人:
Jizeng Qiao,Jeffrey Keeler Teumer,Erica Jean Philips
申请号:
US12293402
公开号:
US08980628B2
申请日:
2007.03.15
申请国别(地区):
US
年份:
2015
代理人:
摘要:
This invention relates to methods of producing hair folliclesin vitro, compositions for producing hair follicles in vitro, in vitro produced hair follicles, methods of providing an in vitro produced hair shaft at an interfollicular or intrafollicular site, methods of treating hair loss by providing an in vitro produced hair shaft at an interfollicular or intrafollicular site and assays for studying the effect of test agents on hair biology. The invention also provides the similar methods and products which are, or use, immature follicles (“defined herein as proto-hairs”). The invention provides a method for in vitro production of a hair follicle or a proto-hair comprising co-culturing dermal papilla cells with keratinocytes, and optionally with melanocytes.