Provided herein are methods for treating and/or preventing a cancer or a tumor syndrome in a patient, comprising administering an effective amount of a TOR kinase inhibitor to a patient having cancer or a tumor syndrome, characterized by a LKB1 and/or AMPK gene or protein loss or mutation.本發明提供治療及/或預防患者之癌症或腫瘤症候群的方法,其包含向具有特徵為LKB1及/或AMPK基因或蛋白損失或突變之癌症或腫瘤症候群的患者投與有效量之TOR激酶抑制劑。(無元件符號說明)