Zmodyfikowana sulfamidaza i jej wytwarzanie

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专利权人:

Swedish Orphan Biovitrum AB (Publ)

发明人:

BERGHARD, CHARLOTTA,NORDLING, ERIK,SVENSSON GELIUS, STEFAN,TJERNBERG, AGNETA

申请号：

PL15713502

公开号：

PL2970413T3

申请日:

2015.04.01

申请国别(地区):

PL

年份:

2018

代理人:

摘要：

Disclosed herein are a modified sulfamidase, a composition comprising a modified sulfamidase, as well as methods for preparing a modified sulfamidase and therapeutic use of such a sulfamidase. In particular, the present disclosure relates to a modified sulfamidase comprising substantially no epitopes for glycan recognition receptors, thereby enabling transportation of said sulfamidase across the blood brain barrier of a mammal, wherein said sulfamidase has catalytic activity in the brain of said mammal.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/