Disclosed are a cartridge (50) and an electronic cigarette with the cartridge (50). The cartridge (50) comprises a cartridge casing (51) having a liquid storage chamber (510); a sealing member (52) for sealing the liquid storage chamber (510); a shielding member, an atomizing chamber (5444), a smoke outlet channel (5443) and air inlet channel arranged on the smoke cartridge casing (51); the atomizing chamber (5444) is in communication with the liquid storage chamber (510), the smoke outlet channel (5443) and the air inlet channel; the sealing member (52) is located between the shielding member and the cartridge casing (51); the shielding member forms part of the outer contour of the cartridge (50) such that the sealing member (52) is shielded by the shielding member; a communication opening (548) is formed in the shielding member; the sealing member (52) is an elastically deformable member; a liquid injection needle (70) passes through the communication opening (548) and the sealing member (52) and then extends into the liquid storage chamber (510) for liquid injection; air in the liquid storage chamber (510) enters the atomizing chamber (5444) and is then discharged via the air inlet channel and/or smoke outlet channel (5443); after the liquid injection needle (70) is pulled out, the sealing member (52) automatically seals the liquid storage chamber (510) again.L'invention concerne une cartouche (50) et une cigarette électronique comprenant la cartouche (50). La cartouche (50) comprend un boîtier de cartouche (51) ayant une chambre de stockage de liquide (510) ; un élément d'étanchéité (52) pour sceller la chambre de stockage de liquide (510) ; un élément de protection, une chambre d'atomisation (5444), un canal de sortie de fumée (5443) et un canal d'entrée d'air agencés sur le boîtier de cartouche de fumée (51) ; la chambre d'atomisation (5444) est en communication avec la chambre de stockage de liquide (510), le canal de sortie de fumée (5443) et le canal d'entr