The present invention relates to a pharmaceutical composition for preventing or treating cancer, the pharmaceutical composition containing a fusion protein comprising p53 protein and p16 protein bound to each other. A pharmaceutical composition according to an embodiment of the present invention can effectively prevent or treat cancer.La présente invention concerne une composition pharmaceutique utile pour prévenir ou traiter le cancer, la composition pharmaceutique contenant une protéine hybride comprenant la protéine p53 et p16 protéine liées lune à lautre. Une composition pharmaceutique selon un mode de réalisation de la présente invention peut efficacement prévenir ou traiter le cancer.p53 단백질 및 p16 단백질이 결합된 융합 단백질을 포함하는 암의 예방 또는 치료용 약학 조성물에 관한 것이다. 일 구체예에 따른 약학 조성물에 따르면, 효과적으로 암의 예방 또는 치료가 가능하다.