Compositions and methods for targeting therapeutic agents to neuromuscular junctions are disclosed. Also disclosed are methods for treating diseases and conditions affecting the neuromuscular junction. Compositions include a neuromuscular junction targeting peptide coupled to a therapeutic agent. Compositions may further include a linker peptide. Methods for targeting therapeutic agents to neuromuscular junctions and treating diseases and conditions affecting the neuromuscular junction include administering a composition including a neuromuscular junction targeting peptide coupled to a therapeutic agent.神経筋接合部に治療薬を標的化する組成物および方法を開示する。神経筋接合部に影響を及ぼす疾患および状態を治療する方法も開示する。組成物は、治療薬に結合した神経筋接合部標的化ペプチドを含む。組成物はさらに、リンカーペプチドを含む。治療薬を神経筋接合部に標的化し、神経筋接合部に影響を及ぼす疾患および状態を治療する方法は、治療薬に結合した神経筋接合部標的化ペプチドを含む組成物を投与することを含む。