Portable ultrasound systems and associated devices and methods for managing power in such systems are disclosed herein. In one embodiment, a method for conserving power in a portable ultrasound system includes disabling one or more first amplifiers and/or at least one or more first analog to digital converters (ADCs) upon initiation of a first pulse repletion interval (PRI). The method further includes, upon initiation of a second PRI, enabling the one or more first amplifiers and/or the one or more of the first ADCs and disabling one or more second amplifiers of and/or one or more second ADCs.