controlled release peptide formulations and methods for increasing charge efficiency and modulating erosion release and initial diffusion rates of a bioactive agent in a polymer based release system
KEVIN BURTON,MIMOUN AYOUB,THOMAS R. TICE,TORSTEN WOEHR
申请号：
BRPI0918820
公开号：
BRPI0918820A2
申请日:
2009.08.28
申请国别(地区):
BR
年份:
2016
代理人:
摘要：
Described herein are methods and compositions for modulating the release and/or drug loading characteristics of encapsulated bioactive agents in polymer-based delivery systems via direct modification of the isoelectric point and/or net charge of the bioactive agent.
