YOU SEUNG KWON,유승권,KANG PHIL JUN,강필준,SON DARYEON,손다련,HONG WON JUN,홍원준,YUN WON JIN,윤원진,LEE JANG BO,이장보,PARK GYU MAN,박규만,KIM IN YONG,김인용,PARK JUNGHYUN,박정현,ZHENG JIE,정걸,GAO WEIWEI,고위위,JANG JI HOON,장지훈,JU,전은경,윤병선
申请号：
KR1020180101208
公开号：
KR1020200024478A
申请日:
2018.08.28
申请国别(地区):
KR
年份:
2020
代理人:
摘要：
The present invention relates to a method for inducing dedifferentiation of neural stem cells from urine cells by introducing mRNA of dedifferentiation factors, Oct4, Sox2, Klf4, and Glis1, and a composition for preventing or treating neurological damage diseases using the neural stem cells induced by the method as an active ingredient. According to the present invention, the clinical availability of the present technique can be improved.COPYRIGHT KIPO 2020본 발명은 역분화 인자 Oct4, Sox2, Klf4 및 Glis1의 mRNA를 도입하여 소변세포로부터 신경줄기세포의 역분화 유도 방법 및 상기 방법에 의해 유도된 신경줄기세포를 유효성분으로 하는 신경 손상 질환 예방 또는 치료용 조성물에 관한 것이다.
