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Cell injury inducing therapeutic drug for use in cancer therapy
专利权人:
Chugai Seiyaku Kabushiki Kaisha
发明人:
Kinoshita, Yasuko,Kawai, Yumiko,Tsunenari, Toshiaki,Ishiguro, Takahiro,Endo, Mika,Sano, Yuji
申请号:
AU2017233658
公开号:
AU2017233658A1
申请日:
2017.02.24
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
The present invention provides: an anticancer drug having, as an active ingredient, a bispecific antibody that contains, in a domain including an antibody variable region that binds to glypican-3 and a domain including an antibody variable region that binds to a T-cell receptor complex, a common L chain capable of improving affinity for both antigens and a pharmaceutical composition that includes the bispecific antibody as an active ingredient and that is for concomitant use with another anticancer drug. The bispecific antibody is a novel and highly-safe molecule having high production efficiency, as well as strong antitumor activity and excellent pharmacokinetics, which is expected to be applied to various cancers.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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