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Coatings with crystallized active agent(s) and methods
专利权人:
SurModics; Inc.
发明人:
Ralph A. Chappa,Kimberly K. M. Lindsoe
申请号:
US14753186
公开号:
US09649413B2
申请日:
2015.06.29
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Embodiments herein include coatings with crystallized active agent(s) and related methods. In an embodiment, a method is included for coating a medical device including selecting a solvent and a polymer, selecting a concentration of an active agent of at least a certain amount of saturation, forming a coating composition having the selected concentration of the active agent, and applying the coating composition to the medical device. In an embodiment, an elution control coating disposed on a medical device is included, the elution control coating including an active agent that is at least about 80% crystallized within one week of being disposed on the medical device. In an embodiment, a method is included for enhancing the formation of active agent crystals within a coating layer including adjusting the concentration of an active agent in a coating solution to reach some percentage of the active agent saturation point.
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