Yanlin WANG-FISCHER,Olga BABICH,Tina GARYANTES,Robert Z. LUO,Srinivasan P. Venkatachalan
申请号:
US15510047
公开号:
US20170304306A1
申请日:
2015.09.08
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Provided herein are methods for treating or preventing prediabetes or diabetes, or maintaining or lowering blood or plasma glucose or maintaining or lowering blood or plasma glycated hemoglobin comprising administering to a subject in need thereof a therapeutically effective amount of a compound selectively inhibiting NaV1.7. In particular, provided herein are processes for the preparation of and intermediates used in the preparation of compounds selectively inhibiting NaV 1.7, such as the compounds of Formula I or compounds of Formula I′: