Waste collection pads are provided which have on their upper surface a waste collection area, the perimeter of the collection area being defined by a self-sealing strip. Suitable self-sealing strips include hook-and-loop, plastic zipper, and adhesive strips. In use, waste is deposited on the waste collection area, and the pad is then folded over so as to functionally engage the self-sealing strips. The waste is thereby contained and substantially sealed off from the environment. An absorbent layer, substantially covering the waste collection area, may optionally be present.